Onycholysis refers to nails lifting from the nail bed. This can stem from medications or harsh substances, but it sometimes flags thyroid issues. The separation often starts at the nail tip and progresses toward the cuticle, forming a cloudy or white patch due to air beneath. Other culprits include psoriasis, fungal infections, injuries, and drugs like tetracycline antibiotics. Regular manicures or long exposure to water can worsen it. Treatment hinges on the cause but often involves keeping affected nails dry and clean, avoiding aggravating activities, and letting the nail regrow naturally. For cases linked to systemic conditions like thyroid disease, addressing the root issue is crucial to stop recurrence.